Contribuição da dieta e água alcalina na redução de complicações da doença renal crônica

Authors

  • Aline Souza Carneiro da Silva
  • Eliane Moreira Vaz Universidade Federal do Rio de Janeiro - Professor aposentado

DOI:

https://doi.org/10.47320/rasbran.2020.1772

Abstract

Currently, alkaline nutritional therapy has raised great discussion in the scientific environment as a factor of renal protection. In order to determine the level of scientific evidence on the influence of diet and alkaline water on the reduction of complications in chronic kidney disease, a review of literature was carried out in six databases: BIREME Virtual Health Library (BVS), PubMed , Web of Science (WoS), SCOPUS and Cochrane Library, using the following keywords: alkaline water, chronic kidney disease / chronic kidney insufficiency, alkaline diet, fruit, vegetables, glomerular filtration rate, potential renal acid load. A total of 1071 references were found. Excluding the duplicates and selecting the articles that deal specifically with the theme, it had totalized 34 articles. After selecting the articles and classifying the type of study, the level of scientific evidence of the articles was determined according to Hood. The studies selected by this review consider that alkaline diets based on fruits and vegetables and the administration of bicarbonate can interfere in the complications of Chronic Renal Disease, such as reducing metabolic acidosis and maintaining the glomerular filtration rate, without being able to find the role of alkaline mineral water in this outcome. However, only 27% of the studies presented more than five scientific evidence, on a scale of one to ten, where ten has the highest scientific evidence and one the lowest. These data point us to the need for more studies with better designs, larger samples, without biases and conflicts of interest.

Downloads

Download data is not yet available.

Author Biography

Eliane Moreira Vaz, Universidade Federal do Rio de Janeiro - Professor aposentado

Graduação em Nutrição pela Universidade do Estado do Rio de Janeiro, mestrado em Nutrição Humana - Universidad de Chile - Chile e doutorado em Nutrição - Universidad de Granada - Espanha. Professora Adjunto IV, aposentada, da Universidade Federal do Rio de Janeiro (UFRJ). Experiência na área de Nutrição, com ênfase em Nutrição Clínica. Professora e orientadora de monografias do Curso de Especialização em Nutrição Clínica da UFRJ. Participou da diretoria da Associação Brasileira de Nutrição - ASBRAN, no período de 2007 a 2014. Nutricionista Clínica.

References

Lugon J R. Doença Renal Crônica no Brasil: um problema de saúde pública. J Bras Nefrol 2009; 31 (Supl 1): 2-5.

Ribeiro RCHM, Oliveira GASA, Ribeiro DF, Bertolin DC, Cesarino CB, Lima LCEQ, Oliveira SM. Caracterização e etiologia da insuficiência renal crônica em uma unidade de nefrologia do interior do Estado de São Paulo. Acta Paul Enferm 2008;21: 207-11. DOI: https://doi.org/10.1590/S0103-21002008000500013

Scialla JJ, Anderson CAM. Dietary acid load: a novel nutritional target in chronic kidney disease? Adv Chronic Kidney Dis 2013; 20(2): 141-9. DOI: https://doi.org/10.1053/j.ackd.2012.11.001

Hsu C, Chertow GM. Elevations of serum phosphorus and potassium in mild to moderate chronic renal insufficiency. Nephrol Dial Transplant 2002; 17: 1419–25. DOI: https://doi.org/10.1093/ndt/17.8.1419

Kraut JA, Kurtz I. Metabolic Acidosis of CKD: Diagnosis, clinical characteristics, and treatment. Am J Kidney Dis 2005; 45: 978–93. DOI: https://doi.org/10.1053/j.ajkd.2005.03.003

Carnaúba RA, Baptistella AB, Paschoal V, Hübscher GH. Diet-induced low-grade metabolic acidosis and clinical outcomes: a review. Nutrients 2017; 9: 538-54. DOI: https://doi.org/10.3390/nu9060538

Remer T. Influence of diet on acid-base balance. Seminars in Dialysis 2000; 13 (4): 221-6. DOI: https://doi.org/10.1046/j.1525-139x.2000.00062.x

Passey C. Reducing the dietary dcid load: how a more alkaline diet benefits patients With Chronic Kidney Disease. Journal of Renal Nutrition 2017; 27(3):151-60. DOI: https://doi.org/10.1053/j.jrn.2016.11.006

Brito-Ashurst I, Varagunam M, Raftery MJ, Yaqoob MM. Bicarbonate supplementation slows progression of CKD and improves nutritional status. J Am Soc Nephrol 2009; 20: 2075–84. DOI: https://doi.org/10.1681/ASN.2008111205

Gątarska A, Tońska E, Ciborska J. Natural mineral bottled waters available on the polish market as a source of minerals for the consumers. Part 1. Calcium and magnesium. Rocz Panstw Zakl Hig 2016; 67(1): 1-8.

Carnauba RA, Moreton MS, Baptistella ABLF, Dantas NM, Santos NS, Naves A, et al. Agua alcalinizante y con alto contenido de magnesio: los posibles efectos beneficiosos para la salud. Actual nutr. 2015; 16(3): 83-9.

Hood PD. Scientific Research and Evidence-Based Practice. San Francisco: WestEd 2003.51p.

Kidney Disease Outcome Quality Initiative - KDOQI clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Am J Kidney Dis 2002; 39(Suppl 2): 1-246.

Bastos MG, Bregma R, Kirsztajn GM. Doença renal crônica: frequente e grave, mas também prevenível e tratável. Rev Assoc Com Bras 2010; 56(2): 248 -53. DOI: https://doi.org/10.1590/S0104-42302010000200028

Carnauba RA, Sussaio MM, Fonseca ABBL, Naves A, Paschoal V, Chaves DFS. Avaliação do potencial alcalinizante das águas minerais comercialmente disponíveis em território brasileiro. Nutrire Rev Soc Bras Aliment Nutr 2015; 40(3): 344-51. DOI: https://doi.org/10.4322/2316-7874.78015

Adamczak M, Masajtis-Zagajewska A, Mazanowska O, Madziarska K, Stompór T, Więcek A. Diagnosis and treatment of metabolic acidosis in patients with chronic kidney disease - position statement of the working group of the Polish Society of Nephrology. Kidney Blood Press Res 2018; 43(3): 959-69. DOI: https://doi.org/10.1159/000490475

Khairallah P, Scialla JJ. Role of acid-base homeostasis in diabetic kidney disease. Current Diabetes Reports 2017; 17(28): 1-11. DOI: https://doi.org/10.1007/s11892-017-0855-6

LEAL VO, JÚNIOR ML, MAFRA D. Acidose metabólica na doença renal crônica: abordagem nutricional. Rev Nutr Campinas 2008; 21(1): 93-103. DOI: https://doi.org/10.1590/S1415-52732008000100010

Yari Z, Mirmiran P. Alkaline diet a novel nutritional strategy in chronic kidney disease? Iranian Journal of Kidney Diseases 2018; 12(4):204-8.

Angéloco RN, Souza A, Romão A, Chiarello G. Alkaline diet and metabolic acidosis: practical approaches to the nutritional management of chronic kidney disease. Journal of Renal Nutrition 2018; 28(3): 215-20. DOI: https://doi.org/10.1053/j.jrn.2017.10.006

Piva JP, Garcia PCR, Martha VF. Distúrbios do equilíbrio ácido-básico. Jornal de Pediatria 1999; 75(Supl.2): 234-43. DOI: https://doi.org/10.2223/JPED.393

Raphael KL, Wei G, Baird BC, Greene T, Beddhu S. Higher. Serum bicarbonate levels within the normal range are associated with better survival and renal outcomes in African Americans. Kidney Int 2010: 356–62. DOI: https://doi.org/10.1038/ki.2010.388

Menon V, Tighiouart H, Vaughn NS, Beck GJ, Kusec jw, Collins AJ, et al. Serum bicarbonate and long-term outcomes in CKD. Am J Kidney Dis 2010: 56: 907–14. DOI: https://doi.org/10.1053/j.ajkd.2010.03.023

Scialla JJ, Appel LJ, Astor BC, Miller ER, Beddhu S, Woodward M, et al. Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease. Clinical Journal of the American Society of Nephrology 2011; 6(7): 1526-32. DOI: https://doi.org/10.2215/CJN.00150111

Siener R. Dietary treatment og metabolic acidosis in chronic kidney disease. Nutrients 2018 (10): 512-518, 31 TIPO DE ESTUDO??? EVIDÊNCIA? DOI: https://doi.org/10.3390/nu10040512

Buclin T, Cosma M, Appenzeller M, Jacquet AF, Décosterd LA, Biollaz J, Burckhardt P. Diet acids and alkalis influence calcium retention in bone. Osteoporos. Int. 2001: 12: 493–99 TIPO DE ESTUDO??? EVIDÊNCIA? DOI: https://doi.org/10.1007/s001980170095

Jehle S, Hulter HN, Krapf R. Effect of potassium citrate on bone density, microarchitecture, and fracture riskin healthy older adults without osteoporosis: A randomized controlled trial. J. Clin. Endocrinol. Metab 2013; 98: 207-17. TIPO DE ESTUDO??? EVIDÊNCIA? DOI: https://doi.org/10.1210/jc.2012-3099

Wynn E, Raetz E, Burckhardt P. The composition of mineral waters sourced from Europe and North America in respect to bone health: composition of mineral water optimal for bone. British Journal of Nutrition 2009; 101(8): 1195-9. DOI: https://doi.org/10.1017/S0007114508061515

Remer T, Manz F. Potential renal acid load of foods and it's influence on urine pH. J Am Diet Assoc 1995; 95: 791-97. DOI: https://doi.org/10.1016/S0002-8223(95)00219-7

Frassetto LA, Todd MK, Júnior MCR, Sebastian A. Estimation of net endogenous noncarbonic acid production in humans from diet potassium and protein contents. J Clin Nutr 1998; 68: 576-83. DOI: https://doi.org/10.1093/ajcn/68.3.576

Goraya N, Simoni J, Jo C, Wesson DE. Dietary acid reduction with fruits and vegetables or bicarbonate attenuates kidney injury in patients with a moderately reduced glomerular filtration rate due to hypertensive nephropathy. Kidney International 2012; 81(1): 86-93. DOI: https://doi.org/10.1038/ki.2011.313

Goraya N, Simoni J, Jo CH, Wesson DE. Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate. Kidney Int 2014; 86: 1031-8. DOI: https://doi.org/10.1038/ki.2014.83

Di Iorio BR, Di Micco L, Marzocco S, De Simone E, De Blasio A, Sirico ML, et al. Very Low-Protein Diet (VLPD) Reduces metabolic acidosis in subjects with chronic kidney disease: The "nutritional light signal" of the renal acid load. Nutrients 2017; 9(1): 69-82. DOI: https://doi.org/10.3390/nu9010069

Goraya N, Wesson DE. Does correction of metabolic acidosis slow chronic kidney disease progression? Curr Opin Nephrol Hypertens 2013; 22(2): 193-7. DOI: https://doi.org/10.1097/MNH.0b013e32835dcbbe

Cupisti A, D'Alessandro C, Gesualdo L, Cosola C, Gallieni M, Egidi MF, et al. Non-Traditional aspects of renal diets: focus on fiber, alkali and vitamin K1 intake. Nutrients 2017; 9(5): 444-59. DOI: https://doi.org/10.3390/nu9050444

Telles C, Boitá ERF. Importância da terapia nutricional com ênfase no cálcio, fósforo, e potássio no tratamento da doença renal crônica. P.Erechim 2015: 39 (145): 143-54.

Wynn E, Krieg MA, Aeschlimann JM, Burckhardt P. Alkaline mineral water lowers bone resorption even in calcium sufficiency: alkaline mineral water and bone metabolism. Bone 2009; 44(1): 120-4. DOI: https://doi.org/10.1016/j.bone.2008.09.007

Sabatier M, Grandvuillemin A, Kastenmayer P, Aeschliman JM, Bouisset F, Arnaud MJ, et al. Influence of the consumption pattern of magnesium from magnesium-rich mineral water on magnesium bioavailability. British Journal of Nutrition 2011; 106: 331–34. DOI: https://doi.org/10.1017/S0007114511001139

Frassetto L, Banerjee T, Powe N, Sebastian A. Acid balance, dietary acid load, and bone effects - A controversial subject. Nutrients 2018; 10: 517-25. DOI: https://doi.org/10.3390/nu10040517

Published

2020-10-13

How to Cite

Silva, A. S. C. da, & Vaz, E. M. (2020). Contribuição da dieta e água alcalina na redução de complicações da doença renal crônica. Revista Da Associação Brasileira De Nutrição - RASBRAN, 11(1), 176–191. https://doi.org/10.47320/rasbran.2020.1772

Issue

Section

Artigos de Revisão

Most read articles by the same author(s)